Tired Always? Poor Liver Health Could Be Behind It

Written by Jillian Lai Mei Siew on Tue, 01 August 2023

Key Highlights

  • It is important to be vigilant of liver health as it is one of the most vital organs in our body responsible for detoxifying, metabolic and immunity functions
  • Constant tiredness and fatigue might be a sign of liver disease and must not be ignored
  • Fatigue may be a symptom  of cholestatic liver disease , which could result from primary biliary cirrhosis and drugs related to liver disease
  • A well-balanced diet and being mindful of foods to have and foods to avoid can go a long way in managing liver health.
  • Here's how fatigue and liver health may be co-related.

Feeling tired all the time is nothing new for most of us adults. Sometimes, we suffer from a dip in energy levels, there are times we crave some extra sleep in the mornings, feel exhausted at work, while doing household chores, or at social gatherings.

However, we do not put too much thought into it, and go about accepting it as part of everyday adult life. But did you know that if this occurs all too frequently, it could be a sign of your liver health being in jeopardy. Shocking, right? Well, let's find out how fatigue and liver might be co-related.

livolin forte

Liver diseases

Now you must be thinking what made your liver do such things? Well, this fatigue is a predominant symptom of cholestatic liver disease in 65% to 85% of patients. Cholestatic liver disease is usually caused by primary biliary cirrhosis (PBC), primary sclerosing cholangitis or drugs related to liver disease.

Fatigue and liver

Okay! Confession time. The pathogenesis of fatigue in general is still not clearly understood. Tiredness or fatigue is not a simple biological procedure, rather it is a complex system affecting nearly up to 20% of our population. But the main problem lies in the difficulties in defining and treating fatigue, so that symptoms are most of the time overlooked or ignored by physicians who care for liver disease patients.

Is the brain involved in any way?

Yes! Of course! Fatigue is caused by changes in neurotransmissions in our brain. Don't be scared by the word neurotransmission. It is just how our brain and nerves interact with each other through various pathways.

Liver disease can cause alterations in the neurotransmitter pathways involved in behavioural activation, arousal and locomotor activity. Some of the neurotransmitters involved are corticotropin-releasing hormone (CRH), serotonin, and noradrenaline. This is why fatigue is often accompanied by anxiety or depression.

Importance of diet and proper nutrition

Let's be honest. There are no magic pills that can solve your problem with fatigue. However, what you can do is to maintain that right balance between different foods and drinks so that your liver works properly and you can cope with the fatigue. The scientific evidence shows that a well-balanced diet is the best way to stay healthy and energetic.

Diet for liver

Enough on your brain, now let's discuss how to keep your liver health in check.

Well, that's easy. All you need is to just eat good foods for the liver. Let's look into the list of foods which you should have and avoid to maintain good liver health.

Foods to haveFoods to avoid
Cruciferous vegetables (Brussels sprouts, broccoli, cauliflower, kale, and mustard greens), Beets, eggs, Green tea, Broccoli, oatmeal, Coffee (2-3 times a day), almond, spinach, blueberries, herbs and spices in a moderate amount, citrus fruits (lemon, lime), garlic, fatty fishSugar, bakery items, Aerated fizzy drinks, alcohol, pizza, pasta, fatty fast foods, high salt food, red meat


As a starting point to managing our liver health, it's important to have good food on our plates to keep away tiredness and be healthy.

Liver disease and fatigue are closely related and we should not neglect symptoms of constant tiredness. Of course there are ways to manage this by avoiding certain foods and including others as described above.


Jillian Lai Mei Siew

As the Product Consultant Manager of Mega BiO-LiFE, Jillian Lai Mei Siew, has the role of providing a productive team spirit among all Product Consultants to equip them with the right health nutritional information. Jillian is a BSc in Nutrition and Community Health, and a MSc in Nutritional Sciences an from Universiti Putra Malaysia. Affiliated to the Professional Affiliation Languages & Dialects Nutrition Society of Malaysia, NSM, Jillian can speak English, Cantonese, Mandarin, Hokkien and Malay.

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